TY - JOUR
T1 - Unusual Ligand Directed Regioselectivity in the Iron Catalyzed Cross Coupling of Allylic Ethers to 2‐Substituted 1,3‐Dienes
AU - Takacs, James M.
AU - Anderson, Lawrence G.
AU - Madhavan, G. V.Bindu
AU - Seely, Franklin L.
PY - 1987/10
Y1 - 1987/10
N2 - C4 of 1 is always preferentially attacked in (L)Fe0‐catalyzed reactions with 2. Whether the product of 1,2 addition, 3, or that of 1,4 addition, 4, predominates depends strongly on L, as does the relative proportion of the products formed by attack on C1; e.g., for R CH2Ph and L 2,2′‐bipyridine, 3:4 = 73:27 (89% of the total yield); for R CH2Ph and L 2,2′‐biquinoline, 3:4 = 6:94 (64%). R CH2Ph, CH2C6H11, tetrahydropyranyl. (Figure Presented.)
AB - C4 of 1 is always preferentially attacked in (L)Fe0‐catalyzed reactions with 2. Whether the product of 1,2 addition, 3, or that of 1,4 addition, 4, predominates depends strongly on L, as does the relative proportion of the products formed by attack on C1; e.g., for R CH2Ph and L 2,2′‐bipyridine, 3:4 = 73:27 (89% of the total yield); for R CH2Ph and L 2,2′‐biquinoline, 3:4 = 6:94 (64%). R CH2Ph, CH2C6H11, tetrahydropyranyl. (Figure Presented.)
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U2 - 10.1002/anie.198710131
DO - 10.1002/anie.198710131
M3 - Article
AN - SCOPUS:84985521805
SN - 0570-0833
VL - 26
SP - 1013
EP - 1015
JO - Angewandte Chemie International Edition in English
JF - Angewandte Chemie International Edition in English
IS - 10
ER -