Uptake of diethylcarbamazine by microfilariae and adults of Litomosoides carinii and Dipetalonema viteae

V. M.L. Srivastavat, D. P. Singh, R. K. Chatterjee, A. B. Sen

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Microfilariae of Litomosoides carinii and Dipetalonema viteae absorbed about ten times as much diethylcarbamazine (DEC) as did their adults, but bound much less. The higher uptake of DEC by the microfilariae might be related to the fact that DEC is microfilaricidal. Binding of DEC with the parasii supports the view that the microfilaricidal action begins with the fixation of the drug to the microfilariae.

Original languageEnglish (US)
Pages (from-to)197-199
Number of pages3
JournalJournal of Helminthology
Volume58
Issue number3
DOIs
StatePublished - Sep 1984
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Animal Science and Zoology

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