Uptake of prolactin from cerebrospinal fluid in rat brain

Steve Landas; Sue Ann Thompson; Rob Lewis; John F. Stamler; Mohan K. Raizada; M. Ian Phillips

doi:10.1016/0143-4179(82)90012-9

Uptake of prolactin from cerebrospinal fluid in rat brain

Steve Landas, Sue Ann Thompson, Rob Lewis, John F. Stamler, Mohan K. Raizada, M. Ian Phillips

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The fate of prolactin in the cerebrospinal fluid was studied by the use of fluorescein labelled prolactin. The distribution was compared to the immunocytochemical distribution of endogenous prolactin. High intensity fluorescence was found in the ependyma of the area postrema, rostral dorsolateral cerebral aqueduct close to the subcommissural organ, and in some cells of the floor of the cerebral aqueduct. This distribution was not seen when excess unlabelled prolactin was injected. The results suggest prolactin uptake from CSF at specific sites which correspond to sites of localization of immunoreactive prolactin.

Original language	English (US)
Pages (from-to)	173-179
Number of pages	7
Journal	Neuropeptides
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/0143-4179(82)90012-9
State	Published - Dec 1982
Externally published	Yes

ASJC Scopus subject areas

Endocrinology
Neurology
Endocrine and Autonomic Systems
Cellular and Molecular Neuroscience

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10.1016/0143-4179(82)90012-9

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title = "Uptake of prolactin from cerebrospinal fluid in rat brain",

abstract = "The fate of prolactin in the cerebrospinal fluid was studied by the use of fluorescein labelled prolactin. The distribution was compared to the immunocytochemical distribution of endogenous prolactin. High intensity fluorescence was found in the ependyma of the area postrema, rostral dorsolateral cerebral aqueduct close to the subcommissural organ, and in some cells of the floor of the cerebral aqueduct. This distribution was not seen when excess unlabelled prolactin was injected. The results suggest prolactin uptake from CSF at specific sites which correspond to sites of localization of immunoreactive prolactin.",

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year = "1982",

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AU - Landas, Steve

AU - Thompson, Sue Ann

AU - Lewis, Rob

AU - Stamler, John F.

AU - Raizada, Mohan K.

AU - Phillips, M. Ian

PY - 1982/12

Y1 - 1982/12

N2 - The fate of prolactin in the cerebrospinal fluid was studied by the use of fluorescein labelled prolactin. The distribution was compared to the immunocytochemical distribution of endogenous prolactin. High intensity fluorescence was found in the ependyma of the area postrema, rostral dorsolateral cerebral aqueduct close to the subcommissural organ, and in some cells of the floor of the cerebral aqueduct. This distribution was not seen when excess unlabelled prolactin was injected. The results suggest prolactin uptake from CSF at specific sites which correspond to sites of localization of immunoreactive prolactin.

AB - The fate of prolactin in the cerebrospinal fluid was studied by the use of fluorescein labelled prolactin. The distribution was compared to the immunocytochemical distribution of endogenous prolactin. High intensity fluorescence was found in the ependyma of the area postrema, rostral dorsolateral cerebral aqueduct close to the subcommissural organ, and in some cells of the floor of the cerebral aqueduct. This distribution was not seen when excess unlabelled prolactin was injected. The results suggest prolactin uptake from CSF at specific sites which correspond to sites of localization of immunoreactive prolactin.

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JO - Neuropeptides

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ER -

Uptake of prolactin from cerebrospinal fluid in rat brain

Abstract

ASJC Scopus subject areas

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