Uptake of prolactin from cerebrospinal fluid in rat brain

Steve Landas, Sue Ann Thompson, Rob Lewis, John F. Stamler, Mohan K. Raizada, M. Ian Phillips

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The fate of prolactin in the cerebrospinal fluid was studied by the use of fluorescein labelled prolactin. The distribution was compared to the immunocytochemical distribution of endogenous prolactin. High intensity fluorescence was found in the ependyma of the area postrema, rostral dorsolateral cerebral aqueduct close to the subcommissural organ, and in some cells of the floor of the cerebral aqueduct. This distribution was not seen when excess unlabelled prolactin was injected. The results suggest prolactin uptake from CSF at specific sites which correspond to sites of localization of immunoreactive prolactin.

Original languageEnglish (US)
Pages (from-to)173-179
Number of pages7
JournalNeuropeptides
Volume3
Issue number2
DOIs
StatePublished - Dec 1982

ASJC Scopus subject areas

  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Uptake of prolactin from cerebrospinal fluid in rat brain'. Together they form a unique fingerprint.

  • Cite this

    Landas, S., Thompson, S. A., Lewis, R., Stamler, J. F., Raizada, M. K., & Phillips, M. I. (1982). Uptake of prolactin from cerebrospinal fluid in rat brain. Neuropeptides, 3(2), 173-179. https://doi.org/10.1016/0143-4179(82)90012-9