@article{216d677c76eb4b8d9c4a268b3b4b6d98,
title = "Urban airborne PM2.5-activated microglia mediate neurotoxicity through glutaminase-containing extracellular vesicles in olfactory bulb",
abstract = "Main finding: Intranasal instillation PM2.5 induces neurotoxicity through its metal contents and glutaminase-containing extracellular vesicles (EVs) in olfactory bulbs of mice.",
keywords = "Extracellular vesicles, Glutamate, Glutaminase, Neurotoxicity, Olfactory bulb, PM",
author = "Xiaoyu Chen and Jing Guo and Yunlong Huang and Shan Liu and Ying Huang and Zezhong Zhang and Fang Zhang and Zhongbing Lu and Fang Li and Zheng, {Jialin C.} and Wenjun Ding",
note = "Funding Information: This study was supported by the Major Program of National Natural Science Foundation of China ( 91643206 , U1432245 to WD), the State Key Program of the National Natural Science Foundation of China ( 81830037 to JZ), the National Institutes of Health : R01 NS097195 (JZ) and the Chinese Academy of Sciences / State Administration of Foreign Experts Affairs International Partnership Program for Creative Research Teams. We thank Yinzi Ma and Pengyan Xia from the State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences (CAS) for their technical assistance. We also thank Fang Li, Shasha Zuo and Dandan Sun from University of Chinese Academy of Science for their kindly help in instrument operation. Funding Information: This study was supported by the Major Program of National Natural Science Foundation of China (91643206, U1432245 to WD), the State Key Program of the National Natural Science Foundation of China (81830037 to JZ), the National Institutes of Health: R01 NS097195 (JZ) and the Chinese Academy of Sciences/State Administration of Foreign Experts Affairs International Partnership Program for Creative Research Teams. We thank Yinzi Ma and Pengyan Xia from the State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences (CAS) for their technical assistance. We also thank Fang Li, Shasha Zuo and Dandan Sun from University of Chinese Academy of Science for their kindly help in instrument operation. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2020",
month = sep,
doi = "10.1016/j.envpol.2020.114716",
language = "English (US)",
volume = "264",
journal = "Environmental Pollution",
issn = "0269-7491",
publisher = "Elsevier Limited",
}