Urinary hexosaminidase in patients with lung carcinoma

M. G. Brattain; P. M. Kimball; J. R. Durant; T. G. Pretlow; D. Smith; J. Carpenter; M. Marks

doi:10.1002/1097-0142(197912)44:6<2267::AID-CNCR2820440640>3.0.CO;2-M

Urinary hexosaminidase in patients with lung carcinoma

M. G. Brattain, P. M. Kimball, J. R. Durant, T. G. Pretlow, D. Smith, J. Carpenter, M. Marks

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The specific activity of urinary hexosaminidase was determined in 58 patients with various histological types of lung carcinoma. Compared to an apparently healthy control population, 32/35 patients with widely disseminated disease showed elevated values and 18/23 patients with disease confined to the chest had normal hexosaminidase values. Detailed studies of 18 patients indicated that declining hexosaminidase values were associated with effective therapy, rising values generally accompanied progressive disease.

Original language	English (US)
Pages (from-to)	2267-2272
Number of pages	6
Journal	Cancer
Volume	44
Issue number	6
DOIs	https://doi.org/10.1002/1097-0142(197912)44:6<2267::AID-CNCR2820440640>3.0.CO;2-M
State	Published - Dec 1979
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(197912)44:6<2267::AID-CNCR2820440640>3.0.CO;2-M

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author = "Brattain, {M. G.} and Kimball, {P. M.} and Durant, {J. R.} and Pretlow, {T. G.} and D. Smith and J. Carpenter and M. Marks",

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AU - Brattain, M. G.

AU - Kimball, P. M.

AU - Durant, J. R.

AU - Pretlow, T. G.

AU - Smith, D.

AU - Carpenter, J.

AU - Marks, M.

PY - 1979/12

Y1 - 1979/12

N2 - The specific activity of urinary hexosaminidase was determined in 58 patients with various histological types of lung carcinoma. Compared to an apparently healthy control population, 32/35 patients with widely disseminated disease showed elevated values and 18/23 patients with disease confined to the chest had normal hexosaminidase values. Detailed studies of 18 patients indicated that declining hexosaminidase values were associated with effective therapy, rising values generally accompanied progressive disease.

AB - The specific activity of urinary hexosaminidase was determined in 58 patients with various histological types of lung carcinoma. Compared to an apparently healthy control population, 32/35 patients with widely disseminated disease showed elevated values and 18/23 patients with disease confined to the chest had normal hexosaminidase values. Detailed studies of 18 patients indicated that declining hexosaminidase values were associated with effective therapy, rising values generally accompanied progressive disease.

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ER -

Urinary hexosaminidase in patients with lung carcinoma

Abstract

ASJC Scopus subject areas

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