Usefulness of Charlson Comorbidity Index to Predict Early Mortality and Overall Survival in Older Patients With Acute Myeloid Leukemia

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1 Scopus citations

Abstract

We hypothesized that higher Charlson comorbidity index (CCI) predicts worse 1-month mortality and overall survival (OS) in patients ≥60 years with acute myeloid leukemia (AML). In our National Cancer Database study, patients with CCI 0 were more likely to receive chemotherapy and undergo upfront hematopoietic cell transplantation. One-month mortality and OS were significantly worse with CCI 1 or ≥2, compared with CCI 0.

Original languageEnglish (US)
Pages (from-to)804-812.e8
JournalClinical Lymphoma, Myeloma and Leukemia
Volume20
Issue number12
DOIs
StatePublished - Dec 2020

Keywords

  • Acute leukemia
  • Chemotherapy
  • Geriatrics
  • Older adults
  • Survival

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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