Introduction: Muscle weakness can be caused by decreases in either the maximum force-generating ability of a muscle (MFGA) or neural drive from the nervous system (e.g., after a stroke). Presently, there is no agreed-upon practical method for calculating the MFGA in individuals with central nervous system pathology. The purpose of this study was to identify the best method for determining MFGA. Methods: The predicted and estimated MFGA of the muscles of 23 non-neurologically impaired subjects (13 males, 21.9 ± 1.9 years) were compared using the burst superimposition, twitch interpolation, doublet interpolation, twitch-to-tetanus ratio, and the adjusted burst superimposition methods. Results: The adjusted burst superimposition test was the most accurate predictor of MFGA. Conclusions: Further testing is needed to validate the use of the adjusted burst superimposition test in a neurologically impaired population.
- Burst superimposition
- Doublet interpolation
- Maximum force-generating ability
ASJC Scopus subject areas
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)