Abstract
Introduction: Muscle weakness can be caused by decreases in either the maximum force-generating ability of a muscle (MFGA) or neural drive from the nervous system (e.g., after a stroke). Presently, there is no agreed-upon practical method for calculating the MFGA in individuals with central nervous system pathology. The purpose of this study was to identify the best method for determining MFGA. Methods: The predicted and estimated MFGA of the muscles of 23 non-neurologically impaired subjects (13 males, 21.9 ± 1.9 years) were compared using the burst superimposition, twitch interpolation, doublet interpolation, twitch-to-tetanus ratio, and the adjusted burst superimposition methods. Results: The adjusted burst superimposition test was the most accurate predictor of MFGA. Conclusions: Further testing is needed to validate the use of the adjusted burst superimposition test in a neurologically impaired population.
Original language | English (US) |
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Pages (from-to) | 849-858 |
Number of pages | 10 |
Journal | Muscle and Nerve |
Volume | 45 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2012 |
Externally published | Yes |
Keywords
- Burst superimposition
- Doublet interpolation
- Maximum force-generating ability
- Twitch
ASJC Scopus subject areas
- Physiology
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)