Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis

Chunyi Zhou; Michael Wiley; Jessica Wiley; Kelly Cawcutt; Elizabeth Grashorn; Kathie Rogers; Emily McCutchen; Peter Iwen; Paul Fey; Mark Rupp

doi:10.1017/ice.2024.240

Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis

Chunyi Zhou, Michael Wiley, Jessica Wiley, Kelly Cawcutt, Elizabeth Grashorn, Kathie Rogers, Emily McCutchen, Peter Iwen, Paul Fey, Mark Rupp

Research output: Contribution to journal › Article › peer-review

Abstract

Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis. WGS, which demonstrated disparate strains, suggested that 42.9% of S. epidermidis CLABSI cases were due to contamination, while clinical review suggested that 57.1% were contamination events.

Original language	English (US)
Journal	Infection Control and Hospital Epidemiology
DOIs	https://doi.org/10.1017/ice.2024.240
State	Accepted/In press - 2025

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.1017/ice.2024.240

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title = "Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis",

abstract = "Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis. WGS, which demonstrated disparate strains, suggested that 42.9% of S. epidermidis CLABSI cases were due to contamination, while clinical review suggested that 57.1% were contamination events.",

author = "Chunyi Zhou and Michael Wiley and Jessica Wiley and Kelly Cawcutt and Elizabeth Grashorn and Kathie Rogers and Emily McCutchen and Peter Iwen and Paul Fey and Mark Rupp",

note = "Publisher Copyright: {\textcopyright} The Author(s), 2025.",

year = "2025",

doi = "10.1017/ice.2024.240",

language = "English (US)",

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T1 - Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis

AU - Zhou, Chunyi

AU - Wiley, Michael

AU - Wiley, Jessica

AU - Cawcutt, Kelly

AU - Grashorn, Elizabeth

AU - Rogers, Kathie

AU - McCutchen, Emily

AU - Iwen, Peter

AU - Fey, Paul

AU - Rupp, Mark

PY - 2025

Y1 - 2025

N2 - Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis. WGS, which demonstrated disparate strains, suggested that 42.9% of S. epidermidis CLABSI cases were due to contamination, while clinical review suggested that 57.1% were contamination events.

AB - Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis. WGS, which demonstrated disparate strains, suggested that 42.9% of S. epidermidis CLABSI cases were due to contamination, while clinical review suggested that 57.1% were contamination events.

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DO - 10.1017/ice.2024.240

M3 - Article

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JO - Infection Control and Hospital Epidemiology

JF - Infection Control and Hospital Epidemiology

ER -

Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis

Abstract

ASJC Scopus subject areas

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