Vaccines: An overview

Santiago M.C. Lopez, Alice I. Sato, Archana Chatterjee

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

Vaccination against infections is one of the greatest advances in medical science, yet often overlooked and underappreciated. From 2010 to 2019, an estimated 37 million lives were saved with vaccination against 10 key pathogens, and that number is expected to rise with improved delivery of these vaccines around the world. Unlike other therapeutic agents, vaccines offer benefits not only to the vaccinated individual directly but can also offer protection to the vaccinated person’s contacts and community. Beyond lives saved, vaccines prevent illness and disability as well, having significant economic impact by decreasing poverty and reducing inequities. This chapter aims to give an overview of different approaches to vaccinology against infectious diseases, review key vaccines in human use, and offer insight into the vaccine development process to ensure safety and efficacy.

Original languageEnglish (US)
Title of host publicationViral, Parasitic, Bacterial, and Fungal Infections
Subtitle of host publicationAntimicrobial, Host Defense, and Therapeutic Strategies
PublisherElsevier
Pages699-717
Number of pages19
ISBN (Electronic)9780323857307
ISBN (Print)9780323898003
DOIs
StatePublished - Jan 1 2022

Keywords

  • Development
  • Immune response
  • Licensing
  • Vaccination
  • Vaccine adjuvants
  • Vaccine indications
  • Vaccines

ASJC Scopus subject areas

  • General Medicine

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