Vacuolar (lysosomal) trehalase of Saccharomyces cerevisiae

Steven D. Harris, David A. Cotter

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


In the yeast Saccharomyces cerevisiae the PEP4 gene product, protease A, is responsible for activating all soluble vacuolar (lysosomal) enzymes. These vacuolar enzymes remain inactive in pep4 mutants. Vacuolar trehalase activity was diminished in such mutants as well. This suggests that the vacuolar (lysosomal) trehalase is processed in a manner similar to other vacuolar enzymes in S. cerevisiae.

Original languageEnglish (US)
Pages (from-to)247-249
Number of pages3
JournalCurrent Microbiology
Issue number5
StatePublished - Sep 1987

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

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