Variable presence of circulating cytokines in patients with sporadic or x-linked lymphoproliferative disease with fatal infectious mononucleosis

Motohiko Okano, Geoffrey M. Thiele, David T. Purtilo

Research output: Contribution to journalLetter

6 Scopus citations

Abstract

Infectious mononucleosis (IM), caused by primary infection of Epstein-Barr virus (EBV), is a self-limiting benign lymphoproliferative disease.1 Rare cases, however, develop severe or fatal IM (SIM or FIM) either sporadically or with X-linked lymphoproliferative disease (XLP).1,2 The pathogenetic mechanism) responsible for SIM or FIM remain unknown mainly owing to the limited number of cases and the difficulties in establishing a precise diagnosis.

Original languageEnglish (US)
Pages (from-to)97-99
Number of pages3
JournalPediatric Hematology and Oncology
Volume10
Issue number1
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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