Variant Translocations of Chromosome 13 in Alveolar Rhabdomyosarcoma

Edwin C. Douglass, Susan T. Rowe, Marc Valentine, David M. Parham, Roger Berkow, W. Paul Bowman, Harold M. Maurer

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


In three cases of alveolar rhabdomyosarcoma with variant translocations, two tumors contained an identical translocation, t(1;13)(p36.1;q14); the third tumor contained a t(8;13)(p21;q14). All three patients were 2 years old, markedly younger than the median age for patients with t(2; 13)‐positive alveolar rhabdomyosarcoma. The alteration of genetic material on chromosome 13 may be of primary importance in the development of alveolar rhabdomyosarcoma.

Original languageEnglish (US)
Pages (from-to)480-482
Number of pages3
JournalGenes, Chromosomes and Cancer
Issue number6
StatePublished - Nov 1991
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Cancer Research


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