Abstract
During testis development, structural changes that are required to create seminiferous tubules rely on the migration of vascular cells from the nearby embryonic kidney into the gonad. This vascular migration occurs along specific pathways to section off areas of the testis and initiate patterning. The cells of the testis communicate with the vascular cells to tell them to migrate, and the vascular cells communicate back to regulate testis cell functions. Thus, testis morphogenesis is a cooperative enterprise undertaken by the host gonad tissue and an immigrant vascular cell population. The established vasculature supports the functionality of the adult testis.
Original language | English (US) |
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Title of host publication | Encyclopedia of Reproduction |
Publisher | Elsevier |
Pages | 47-52 |
Number of pages | 6 |
ISBN (Electronic) | 9780128151457 |
DOIs | |
State | Published - Jan 1 2018 |
Keywords
- Cell signaling
- Development
- Endothelial
- Male
- Migration
- Morphogenesis
- Reproductive system
- Testis
- Vascular endothelial growth factor
- Vasculature
ASJC Scopus subject areas
- General Medicine