Vertebral vacuum phenomenon - A radiographic manifestation of metastatic malignancy

Stephen I. Schabel, Timothy E. Moore, Gerald M. Rittenberg, John H. Stanley, Leighton H. Javid

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Gas lucency within intervertebral disc spaces, the vertebral vacuum phenomenon (VVP) was visible radiographically in 12/42 (28%) women with adenocarcinoma of the breast metastatic to bone. In 7/12 (17%) the VVP occurred adjacent to vertebra involved with metastatic tumor and free of significant degenerative changes. Vertebral collapse occurred in all seven women, but was minimal in some when the VVP was prominent. Metastatic malignancy should be considered along with degenerative disease when the VVP is observed.

Original languageEnglish (US)
Pages (from-to)154-156
Number of pages3
JournalSkeletal Radiology
Issue number3
StatePublished - Sep 1979
Externally publishedYes


  • Intervertebral disc, radiography
  • Intervertebral disc, vacuum phenomenon
  • Vertebra, metastatic tumor

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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