Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences

J. A. Johnson; C. A. Salles; P. Panigrahi; M. J. Albert; A. C. Wright; R. J. Johnson; J. G. Morris

Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences

J. A. Johnson, C. A. Salles, P. Panigrahi, M. J. Albert, A. C. Wright, R. J. Johnson, J. G. Morris

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pandemic strains, as shown by multilocus enzyme electrophoresis, Bengal strains are encapsulated and portions of the O1 antigen biosynthetic complex genes found in O1 strains are altered or lacking. Encapsulated Bengal strains showed resistance to killing by normal human serum. The presence of the capsule suggests the potential for bloodstream invasion in susceptible hosts and has profound implications for vaccine development.

Original language	English (US)
Pages (from-to)	2108-2110
Number of pages	3
Journal	Infection and immunity
Volume	62
Issue number	5
State	Published - 1994
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

Cite this

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title = "Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences",

abstract = "Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pandemic strains, as shown by multilocus enzyme electrophoresis, Bengal strains are encapsulated and portions of the O1 antigen biosynthetic complex genes found in O1 strains are altered or lacking. Encapsulated Bengal strains showed resistance to killing by normal human serum. The presence of the capsule suggests the potential for bloodstream invasion in susceptible hosts and has profound implications for vaccine development.",

author = "Johnson, {J. A.} and Salles, {C. A.} and P. Panigrahi and Albert, {M. J.} and Wright, {A. C.} and Johnson, {R. J.} and Morris, {J. G.}",

year = "1994",

language = "English (US)",

volume = "62",

pages = "2108--2110",

journal = "Infection and immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "5",

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TY - JOUR

T1 - Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences

AU - Johnson, J. A.

AU - Salles, C. A.

AU - Panigrahi, P.

AU - Albert, M. J.

AU - Wright, A. C.

AU - Johnson, R. J.

AU - Morris, J. G.

PY - 1994

Y1 - 1994

N2 - Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pandemic strains, as shown by multilocus enzyme electrophoresis, Bengal strains are encapsulated and portions of the O1 antigen biosynthetic complex genes found in O1 strains are altered or lacking. Encapsulated Bengal strains showed resistance to killing by normal human serum. The presence of the capsule suggests the potential for bloodstream invasion in susceptible hosts and has profound implications for vaccine development.

AB - Although Vibrio cholerae O139 synonym Bengal strains, from the current epidemics in India and Bangladesh, are closely related to seventh-pandemic strains, as shown by multilocus enzyme electrophoresis, Bengal strains are encapsulated and portions of the O1 antigen biosynthetic complex genes found in O1 strains are altered or lacking. Encapsulated Bengal strains showed resistance to killing by normal human serum. The presence of the capsule suggests the potential for bloodstream invasion in susceptible hosts and has profound implications for vaccine development.

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UR - http://www.scopus.com/inward/citedby.url?scp=0028294432&partnerID=8YFLogxK

M3 - Comment/debate

C2 - 8168977

AN - SCOPUS:0028294432

SN - 0019-9567

VL - 62

SP - 2108

EP - 2110

JO - Infection and immunity

JF - Infection and immunity

IS - 5

ER -

Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences

Abstract

ASJC Scopus subject areas

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