vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus

Agriculture & Biology

• Human immunodeficiency virus 1 100%
• macrophages 72%
• monocytes 68%
• viruses 52%
• mutants 14%
• pathogenicity 13%
• infection 12%
• DNA 12%
• missense mutation 10%
• sequence deletion 10%
• viral load 9%
• T-lymphocytes 7%
• enzyme-linked immunosorbent assay 6%
• quantitative polymerase chain reaction 6%
• antigens 6%
• cell lines 6%
• sucrose 5%
• mutation 5%
• RNA 5%
• synthesis 4%
• genes 2%
• cells 2%

Medicine & Life Sciences

• HIV-1 70%
• Macrophages 57%
• Viruses 54%
• Viral DNA 27%
• Viral Load 15%
• vif Genes 11%
• Infections 11%
• Viral Antigens 9%
• Sequence Deletion 9%
• Viral RNA 8%
• Missense Mutation 8%
• Coculture Techniques 8%
• Sucrose 7%
• Immunoprecipitation 7%
• Enzyme-Linked Immunosorbent Assay 5%
• Maintenance 5%
• T-Lymphocytes 5%
• Cell Line 4%
• Polymerase Chain Reaction 4%
• Mutation 4%