Viral agents of human disease: Biosafety concerns

Michelle Rozo, James Lawler, Jason Paragas

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter discusses the unique hazards of handling biosamples that contain viruses and the illnesses that can result from occupational exposure and infection. Basic concepts of virology and clinical syndromes of viral infections are reviewed, with specific attention dedicated to viral pathogens associated with a risk of work-acquired infections. The last section addresses laboratory safety challenges presented by newer biotechnologies. Armed with the knowledge presented in this chapter, the laboratorian will be able to define a risk management matrix based on the risk of a virus in a specimen from a patient manifesting a specific illness, the types of procedures used in the laboratory, and the potential outcome of a laboratory-acquired infection (LAI).

Original languageEnglish (US)
Title of host publicationBiological Safety
Subtitle of host publicationPrinciples and Practices
Number of pages34
ISBN (Electronic)9781683670643
ISBN (Print)9781555816209
StatePublished - Jan 1 2016
Externally publishedYes


  • Acute gastroenteritis
  • Acute neurologic disorder
  • Arboviral epidemiology
  • Gain-of-function virus
  • Laboratory-acquired infection
  • Viral epidemiology
  • Virology

ASJC Scopus subject areas

  • Immunology and Microbiology(all)


Dive into the research topics of 'Viral agents of human disease: Biosafety concerns'. Together they form a unique fingerprint.

Cite this