Abstract
This chapter discusses the unique hazards of handling biosamples that contain viruses and the illnesses that can result from occupational exposure and infection. Basic concepts of virology and clinical syndromes of viral infections are reviewed, with specific attention dedicated to viral pathogens associated with a risk of work-acquired infections. The last section addresses laboratory safety challenges presented by newer biotechnologies. Armed with the knowledge presented in this chapter, the laboratorian will be able to define a risk management matrix based on the risk of a virus in a specimen from a patient manifesting a specific illness, the types of procedures used in the laboratory, and the potential outcome of a laboratory-acquired infection (LAI).
| Original language | English (US) |
|---|---|
| Title of host publication | Biological Safety |
| Subtitle of host publication | Principles and Practices |
| Publisher | wiley |
| Pages | 187-220 |
| Number of pages | 34 |
| ISBN (Electronic) | 9781683670643 |
| ISBN (Print) | 9781555816209 |
| DOIs | |
| State | Published - Jan 1 2016 |
| Externally published | Yes |
Keywords
- Acute gastroenteritis
- Acute neurologic disorder
- Arboviral epidemiology
- Gain-of-function virus
- Laboratory-acquired infection
- Viral epidemiology
- Virology
ASJC Scopus subject areas
- General Immunology and Microbiology