Viral Hemorrhagic Fever Preparedness

Angela Hewlett; Angela M. Vasa; Ted Cieslak; John-Martin J Lowe; Michelle Schwedhelm

doi:10.1007/978-3-030-98427-4_21

Viral Hemorrhagic Fever Preparedness

Angela Hewlett, Angela M. Vasa, Ted Cieslak, John-Martin J Lowe, Michelle Schwedhelm

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The 2014-2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. Moreover, the 2014-2016 outbreak was the first in which patients, albeit few in number, were afforded sophisticated intensive care in the United States and in Europe. This ‘high-level containment care’ (HLCC) was provided in specially designed, purpose-built biocontainment units (BCUs). Since the 2014-2016 outbreak and as of this writing, multiple EVD outbreaks have occurred in the Democratic Republic of the Congo as well as a single outbreak in Guinea, emphasizing the need for continued preparedness. In this chapter we explore the history and evolution of biocontainment, discuss its unique engineering and infection control modalities, and offer recommendations for the clinical and operational management of Ebola and other viral hemorrhagic fevers (VHFs).

Original language	English (US)
Title of host publication	Infection Prevention
Subtitle of host publication	New Perspectives and Controversies: Second Edition
Publisher	Springer International Publishing
Pages	237-252
Number of pages	16
ISBN (Electronic)	9783030984274
ISBN (Print)	9783030984267
DOIs	https://doi.org/10.1007/978-3-030-98427-4_21
State	Published - Jan 1 2022

Keywords

Biocontainment
Ebola
Hospital preparedness
Outbreak
VHF
Viral hemorrhagic fever

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-030-98427-4_21

Cite this

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abstract = "The 2014-2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. Moreover, the 2014-2016 outbreak was the first in which patients, albeit few in number, were afforded sophisticated intensive care in the United States and in Europe. This {\textquoteleft}high-level containment care{\textquoteright} (HLCC) was provided in specially designed, purpose-built biocontainment units (BCUs). Since the 2014-2016 outbreak and as of this writing, multiple EVD outbreaks have occurred in the Democratic Republic of the Congo as well as a single outbreak in Guinea, emphasizing the need for continued preparedness. In this chapter we explore the history and evolution of biocontainment, discuss its unique engineering and infection control modalities, and offer recommendations for the clinical and operational management of Ebola and other viral hemorrhagic fevers (VHFs).",

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AU - Cieslak, Ted

AU - Lowe, John-Martin J

AU - Schwedhelm, Michelle

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

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N2 - The 2014-2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. Moreover, the 2014-2016 outbreak was the first in which patients, albeit few in number, were afforded sophisticated intensive care in the United States and in Europe. This ‘high-level containment care’ (HLCC) was provided in specially designed, purpose-built biocontainment units (BCUs). Since the 2014-2016 outbreak and as of this writing, multiple EVD outbreaks have occurred in the Democratic Republic of the Congo as well as a single outbreak in Guinea, emphasizing the need for continued preparedness. In this chapter we explore the history and evolution of biocontainment, discuss its unique engineering and infection control modalities, and offer recommendations for the clinical and operational management of Ebola and other viral hemorrhagic fevers (VHFs).

AB - The 2014-2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. Moreover, the 2014-2016 outbreak was the first in which patients, albeit few in number, were afforded sophisticated intensive care in the United States and in Europe. This ‘high-level containment care’ (HLCC) was provided in specially designed, purpose-built biocontainment units (BCUs). Since the 2014-2016 outbreak and as of this writing, multiple EVD outbreaks have occurred in the Democratic Republic of the Congo as well as a single outbreak in Guinea, emphasizing the need for continued preparedness. In this chapter we explore the history and evolution of biocontainment, discuss its unique engineering and infection control modalities, and offer recommendations for the clinical and operational management of Ebola and other viral hemorrhagic fevers (VHFs).

KW - Biocontainment

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KW - Hospital preparedness

KW - Outbreak

KW - VHF

KW - Viral hemorrhagic fever

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Viral Hemorrhagic Fever Preparedness

Abstract

Keywords

ASJC Scopus subject areas

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