Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets

Oliver Lazarus, Thomas W. Woolerton, Alison Parkin, Michael J. Lukey, Erwin Reisner, Javier Seravalli, Elizabeth Pierce, Stephen W. Ragsdale, Frank Sargent, Fraser A. Armstrong

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


(Chemical Equation Presented) The water-gas shift (WGS) reaction (CO + H2O CO2 + H2) is of major industrial significance in the production of H2 from hydrocarbon sources. High temperatures are required, typically in excess of 200°C, using d-metal catalysts on oxide supports. In our study the WGS process is separated into two half-cell electrochemical reactions (H+ reduction and CO oxidation), catalyzed by enzymes attached to a conducting particle. The H + reduction reaction is catalyzed by a hydrogenase, Hyd-2, from Escherichia coli, and CO oxidation is catalyzed by a carbon monoxide dehydrogenase (CODH I) from Carboxydothermus hydrogenoformans. This results in a highly efficient heterogeneous catalyst with a turnover frequency, at 30°C, of at least 2.5 s-1 per minimum functional unit (a CODH/Hyd-2 pair) which is comparable to conventional high-temperature catalysts.

Original languageEnglish (US)
Pages (from-to)14154-14155
Number of pages2
JournalJournal of the American Chemical Society
Issue number40
StatePublished - Oct 14 2009

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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