Wear, Osteolysis, and Aseptic Loosening Following Total Hip Arthroplasty in Young Patients with Highly Cross-Linked Polyethylene: A Review of Studies with a Follow-Up of over 15 Years

Christopher F. Deans, Brandt C. Buckner, Kevin L. Garvin

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Total hip arthroplasty (THA) has in recent years trended toward a younger, more physically demanding patient population. Mid- to long-term studies of all ages of THA patients using highly cross-linked polyethylene (HXLPE) have been favorable, but concerns about its long-term failure and wear-related complications remain for young THA patients. In this narrative review, a search of the PubMed/MEDLINE and Cochrane databases was performed, and we identified six studies with a minimum 15-year follow-up of HXLPE with various femoral head materials. Wear-related revisions were exceedingly low for patients under the age of 55, with variable reports of non-clinically significant osteolysis. Higher activity levels, a larger femoral head size, and femoral head material were not associated with greater long-term wear rates. Young THA with metal or ceramic on HXLPE is exceedingly durable with favorable outcomes at follow-ups of over 15 years.

Original languageEnglish (US)
Article number6615
JournalJournal of Clinical Medicine
Volume12
Issue number20
DOIs
StatePublished - Oct 2023

Keywords

  • highly cross-linked polyethylene
  • polyethylene wear
  • total hip arthroplasty
  • young arthroplasty

ASJC Scopus subject areas

  • General Medicine

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