Abstract
In this paper we construct a mathematical model for DNA replication based on Shannon's mathematical theory for communication. We treat DNA replication as a communication channel. We show that the mean replication rate is maximal with four nucleotide bases under the primary assumption that the pairing time of the G-C bases is between 1.65 and 3 times the pairing time of the A-T bases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 727-733 |
| Number of pages | 7 |
| Journal | Bulletin of Mathematical Biology |
| Volume | 68 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 2006 |
Keywords
- Base pairing time
- Communication channel
- DNA replication
- Data rate
ASJC Scopus subject areas
- General Neuroscience
- Immunology
- General Mathematics
- General Biochemistry, Genetics and Molecular Biology
- General Environmental Science
- Pharmacology
- General Agricultural and Biological Sciences
- Computational Theory and Mathematics