Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

Željka Korade; Károly Mirnics

doi:10.1016/j.neuron.2011.09.002

Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

Željka Korade, Károly Mirnics

Research output: Contribution to journal › Short survey › peer-review

12 Scopus citations

Abstract

Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

Original language	English (US)
Pages (from-to)	955-957
Number of pages	3
Journal	Neuron
Volume	71
Issue number	6
DOIs	https://doi.org/10.1016/j.neuron.2011.09.002
State	Published - Sep 22 2011
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2011.09.002

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@article{01791369e6b54d94875f6a5472d45412,

title = "Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia",

abstract = "Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.",

author = "{\v Z}eljka Korade and K{\'a}roly Mirnics",

year = "2011",

month = sep,

day = "22",

doi = "10.1016/j.neuron.2011.09.002",

language = "English (US)",

volume = "71",

pages = "955--957",

journal = "Neuron",

issn = "0896-6273",

publisher = "Cell Press",

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TY - JOUR

T1 - Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

AU - Korade, Željka

AU - Mirnics, Károly

PY - 2011/9/22

Y1 - 2011/9/22

N2 - Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

AB - Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

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U2 - 10.1016/j.neuron.2011.09.002

DO - 10.1016/j.neuron.2011.09.002

M3 - Short survey

C2 - 21943593

AN - SCOPUS:80053129862

SN - 0896-6273

VL - 71

SP - 955

EP - 957

JO - Neuron

JF - Neuron

IS - 6

ER -

Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

Abstract

ASJC Scopus subject areas

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